Alex: Well, what if the interstate gets moved entirely, civilisations create everything we need on that side of it.
Dr Sherlin: That’s exactly right.
Alex: Yeah, I think in the article actually it’s referenced that a situation a woman was born without a right hemisphere, her left hemisphere rated a lot less than it needed to survive without the right hemisphere is really good.
Dr Sherlin: That’s right. And that really leads into the whole conversation that it’s a complicated around injury and degenerative diseases because it depends on the severity and it depends on the ideology. In the absence of having a particular lobotomy or having an absence area or some tissue removed clearly it’s a very different scenario where we’re trying to augment and enhance the efficiency and remaining cells instead of trying to rehabilitate so it’s a very complex people for picture. Much of this type of process is very similar
Alex: And that actually kind of leads me just to a follow up question just on that sort of victim. In the age limit that you’ve found and that other research suggests for any type of rehabilitation of the brain is left to be determined.
Dr Sherlin: Yeah I think I can. Well there certainly hasn’t been a certain limit when you’re over X age then you might as well just forget about it. You’re not going to… But we also know that the younger we are the more likely we are at having, you know more production of cells and you know, neurogenesis is a much more faster rate the younger we are, so age is a factor. But I don’t think that we should give up on anybody at any particular age. Because the evidence suggests, even at an age the elder population there is still this process occurring. So certainly we’ve seen it in some of our clients who had dementia or cognitive or has alzheimer’s. There’s Some progress to be made if nothing else then reducing the rate or speed at which degeneration occurs
Alex: Since – like the rest of our bodies it heals faster the younger we are. Okay so let’s talk about stress real quick. Chronic levels of stress if really important in the article, chronic levels of stress increased baseline levels of cortisol which decreases the production of stem cells and then that depresses the mood at high levels the resolve is produced by long term stress which decreases neurogenesis if it shows up on an MRI looking like Alzheimer’s because it is a shrunken cerebral cortex. I know that I deal with anxiety and stress when I feel I am able to solve innovative problem when I work on relationships small challenges are athletes we’re talking former CEO’s etcetera etcetera I deal with on an everyday basis. So the question to you would be, do you have any case studies that you’d like to reference from your clinic where you can attribute a decrease in neurogenesis from the constant stress on your athlete’s brain after years of competition or tough decisions.
Dr Sherlin: Yeah, so that’s a bit of a tricky question, it’s a very good and relevant question. But as most of the healthy individuals that come in that I get to encounter we’re not doing a lot of heavy structural imaging and those types of things, so you know it would be, it’s uncertain how much and to what degree there is a structural impact from all of these high stressers across time we much more aware of all the different emotional kind of aspects and the cognitive kinds of aspects that you mentioned. It would certainly seem that reflected in the electricle activity in the brain in the way that it’s much less invasive and a much more cost effective way of imaging and so that’s the modality that we use for imaging. We do certainly see that indviuals who have a higher level of cronic stress or anxiety do have deminisiing capacities where the capacity for performing everyday kidns of functions just as you’re alluded to, some of that is on an accute basis, we’re just simply, we’re processing that information so whatever the stressers or the stimuli are we’re heavily involved in managing our resources to managing that and so it’s just less availability, less attentionspan so to speak or focus ability for that particular aspect. But on a chronic or a long term exposure we start to see those patterns continue, even when the stresser is removed and so, there is this emotional and cognitive type of area over that even after the components come so there are lot’s of clinical patients who’ve come in and they have a what we might call burn out syndrome or a chronic fatigue even that comes on and now theres no immediate explination for why they’re experiencing the chronic fatigue or perhaps even the physical pain that can also go along with that. But it’s just from long term exposure to that are stressors or high levels of cortisol which are fatiguing a drane glands and finally they have a collapse, we see this a lot from high performers because they are constantly pushing themselves at that edge then when finally the system gives out the system has given out we’ve seen both also imagine we’ve also – a different population that have very high levels of exposure, we get to evaluate groups of soldiers and those who have been exposed to combat that stressors to perform over a longer period of time and perform at a lesser levels from cognitive strategies on cognitive strategies. So there’s some residual that occurs and so the training can help modulate and even providing the system with – the physical system with lots of support is necessary for a long period, so it’s – it can be quite detrimental to performance for those – even for those who are the highest performers after having chronic exposure.