Alex: Okay. So yeah, it’s safe to say that neurogenesis does decrease after prominent levels of stress you and cortisol it is just kind of at a constant state where genesis suffers from that.
Dr Sherlin: Right. It’s very much the same, as we spoke about the state, the stress, re thoughts were constantly we are in that fight or flight moment it’s not about – it’s about self preservation in the moment and those other types of processes take a back seat and that’s one – one of the consequences is even neurogenesis and in fact it can be quite a refractory period that has to occur before we start to see things normalize.
Alex: Yeah, okay okay great answers to the questions. Almost done here, two more questions and then we’ll wrap up. So you touched on this, I think you actually did answer this but the second question I had follows up to that. But what part of brain training in a drop off of neurogenesis? And diseases like alzheimer’s and dementia and neuron. It’s not a huge part of the clinic, it’s incorporate now and you guys are more focused on the athletes and performers and obviously brain training plays a big role in the prevention of alzheimer’s and dementia. But kind of trying to bring, well, obviously does bring that in play like you mentioned earlier so if you could touch on the role that brain training plays on intervention? The drop off in neurogenesis.
Dr Sherlin: Absolutely. So what we know is certainly that you know, the ideology and the degeneration occurs at some rate and for differing individuals, that rate varies. So we – what we do know is that keeping a high level of engagement from the neuronal type of activities so more than just doing crossword puzzles. In fact what that does for our brain is the important piece around that neuronal firing and keeping that active. If not warding off or slowing the actual development of the degeneration, increasing the neurogenesis to hone it so that what we see is a longer – unset – a longer time period from diagnosis to each of the stages of symptom tollegies so that what that ultimately means to you know the client is that they’re going to be able to increase the overall cognitive function and minimize the negative impact of quality live by keeping the brain in a healthier state so it’s just like any other type of degenerative disorder that we might have imagined from a physical standpoint from the neck down, you know keeping our body healthy and muscles strong and bones, you know, fortified is going to, you know, slow down that progression and increase, you know the overall quality as we fight off these symptoms.
Alex: Okay, so training the brain to be able to combat stressors and view the stress factors leads to unlocking that potential instruction of neurogenesis by the release of constant contrast which can lead to obviously inevitably possible diseases like alzheimer’s and dementia because the neurogenesis is locked by those pressures. So you will be able to train the brain to you know, combat those stressors and often keep the brain healthy and then happy and prevent alzheimer’s and dementia.
Dr Sherlin: Yeah, absolutely. There’s this model, it’s an old one but it’s a good one kind of thing and it still certainly has some relevance in the diapedesis stress model which is basically is that you know, we have some basic prediscovery or some occurrence of a disease or pathology that is, you know. We’re predisposed for that. But it’s not until it reaches a certain level that it actually has an impact on us and so we see this from a physical attributes as well as mental aspects. We can do lots of neuroimaging and say someone, you know, they have the brain that looks like they’re depressed or in an attempt to fill in the blank but they don’t experience those symptoms, it’s not until there’s a significant level of stress or impact that causes the symptoms to manifest and sometimes that’s symptoms and when they do can be quite overwhelming. Comes as a rapid onset, we might even say so you know, this process of keeping our stressors managed or keeping our brain healthy and engaged and it raises that threshold of which we might become a victim or succumb you know, to the symptom presentation.
Quotes from the article:
“Research in 2008 showed that stem cells in the hippocampus survive better and flourish in correlation to increased mental effort. And, when greater numbers of stem cells mature, they produce higher levels of serotonin, that then lead to positive moods and joyful emotions.”
The section goes on to say: “Brain exercises that produce more stem cells also slow both onset and progression of degenerative brain diseases (like Alzheimers and Dementia). One researcher has proposed that challenging brain exercises also elevate mood better than pharmaceuticals.” Read the full article on Neurogenesis and Brain Plasticity >>>
“With steady effort and application, the adult brain can re-train itself by rewiring its connections. This becomes necessary after parts die off in circumstances like stroke, tumor surgery, or traumatic accidents. The earlier in life the damage, the greater the potential for self-repair.” Read the full article on Neurogenesis and Brain Plasticity >>>
“Chronic levels of stress increases baseline levels of cortisol which decreases the production of stem cells and depresses our mood. At high levels, the cortisol produced by long-term stress decreases neurogenesis and even shows up on an MRI looking like Alzheimer’s disease – as a shrunken cerebral cortex.” Read the full article on Neurogenesis and Brain Plasticity >>>
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